Generic Medications Used to Treat ADHD

Prescription pills spill out of medication bottle on a counter.

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Attention-deficit/hyperactivity disorder (ADHD) is commonly diagnosed in children, often persisting through adolescence and later adulthood. While many brand-name drugs are available to help treat ADHD in people of all ages, generic alternatives may be more affordable—if they're not already required by your insurance provider.

Common ADHD Medications

Medications are a big part of ADHD treatment for both adults and children, and a majority of the brand name options are also available as generic drugs. Common ADHD medications can be divided into two main categories: stimulants and non-stimulants.

Stimulant ADHD Medications

Prescription ADHD stimulants work by slowly and steadily increasing the level of dopamine in the brain. This provides positive effects related to movement and attention.

Several brand-name stimulants are used to help treat ADHD. Here are some of the most common ADHD stimulants and their generics, which are listed in parenthesis:

  • Adderall and Adderall XR (amphetamine-dextroamphetamine is a generic name for Adderall, also sometimes referred to as amphetamine/dextroamphetamine salts)
  • Concerta (methylphenidate)
  • Daytrana (methylphenidate)
  • Dexedrine (dextroamphetamine)
  • Dyanavel XR (amphetamine)
  • Focalin and Focalin XR (dexmethylphenidate)
  • Metadate CD (methylphenidate)
  • Methylin and Methylin ER (methylphenidate)
  • Ritalin and Ritalin LA (methylphenidate)
  • Quillivant XR (methylphenidate)
  • Vyvanse (lisdexamfetamine)

The XR, ER, and LA designations indicate extended-release preparations.

Non-Stimulant ADHD Medications

Non-stimulant medications may also be prescribed for ADHD treatment when an individual does not respond well to stimulant drugs. Non-stimulant ADHD medications and their generics include:

  • Intuniv (guanfacine)
  • Kapvay (clonidine)
  • Strattera (atomoxetine)
  • Qelbree (viloxazine)

Cost of Brand Name vs. Generic ADHD Drugs

Brand-name drugs can be expensive, with generic medications often being lower-cost alternatives. In fact, the FDA reports that the cost of generic medications is typically around 85% less than that of brand-name options when there are multiple generics for the same drug on the market.  

While this doesn't reflect the potential savings for every generic medication, particularly when there are fewer generic competitors, in many instances, switching to generic medications can save you hundreds or thousands of dollars on ADHD treatment each year.

Additionally, although it may be more convenient to take extended-release versions of ADHD drugs because fewer doses are needed, these formulations are generally more expensive. So, you may save money by using shorter-acting generics instead.

Medication costs can also be dependent on the pharmacy you use and your insurance coverage. Some insurance companies only authorize brand-name drugs while others only authorize generics. Factors such as these can impact how much you pay for your ADHD medications.

Are Generic ADHD Drugs Effective?

Some people are concerned about the effectiveness of generic ADHD medications versus brand-name options. It's important to know that each generic medication goes through the same level of scrutiny and approval process by the Food and Drug Administration (FDA).

The FDA states, "A generic medicine works in the same way and provides the same clinical benefit as its brand-name version." In order to be approved for use, it has to have the same safety, strength, quality, performance, and intended use.

Notably, the FDA withdrew approval of two generic versions of Concerta (methylphenidate hydrochloride) extended-release (ER) capsules, as they failed to demonstrate the same therapeutic effect as the brand-name drug.

Changing ADHD Medications

As with any type of medication, some people may not have the same reaction to a generic drug as they do to the brand name equivalent (or vice versa). Therefore, it's important to pay attention to any noticeable changes when switching ADHD medications.

Bring up anything you notice—including side effects—to your healthcare provider so they can make adjustments as needed. This may include a dosage change or trying a different medication until you find the right one for you. ADHD is a very individual condition and requires individualized treatments.

ADHD Medication Side Effects

Some of the most common ADHD medication side effects include decreased appetite, trouble sleeping, anxiety, upset stomach, and changes in blood pressure or heart rate. If these effects don't go away after a couple of weeks or are bothersome, talk with the prescribing physician about your options.

Payment Support for ADHD Medications

If you're having trouble paying for ADHD medications, talk to your healthcare provider about generic alternatives that may be available. Your physician may be able to offer you options that can lower the cost of your ADHD medications.

For example, many large pharmacy retailers offer a value formulary, which is a list of medications that can be prescribed for less cost. Prescription assistance programs are also available in many communities and can subsidize the cost of treatment.

Summary

Treating ADHD with medications often requires patience and open conversations with your healthcare provider. If you have concerns over the cost of medications, bring these up during your appointments, along with any questions you have about side effects. By working together, you can find a treatment that is best suited for you.

6 Sources
Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. National Institute on Drug Abuse. Stimulant ADHD medications: methylphenidate and amphetamines.

  2. Shier AC, Reichenbacher T, Ghuman HS, Ghuman JK. Pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: clinical strategies. J Cent Nerv Syst Dis. 2013;5:1-17. doi:10.4137/JCNSD.S6691

  3. Food and Drug Administration. Generic drug facts.

  4. Food and Drug Administration. Generic competition and drug prices: New evidence linking greater generic competition and lower generic drug prices.

  5. Food and Drug Administration. Methylphenidate hydrochloride extended release tablets (generic Concerta) made by Mallinckrodt and Kudco.

  6. Cleveland Clinic. ADHD medication.

By Michael Bihari, MD
Michael Bihari, MD, is a board-certified pediatrician, health educator, and medical writer, and president emeritus of the Community Health Center of Cape Cod.