During the 1960s, 1970s, and 1980s, tricyclic antidepressants were the most commonly used drugs to treat depression. Since then, they have largely been replaced by a class of antidepressant medications known as the SSRIs, which includes such medications as Lexapro (escitalopram), Paxil (paroxetine), and Zoloft (sertraline).
- amitriptyline (Elavil, Endep)
- amoxapine (Asendin)
- clomipramine (Anafranil)
- desipramine (Norpramin)
- doxepin (Sinequan)
- imipramine (Tofranil)
- maprotiline (Ludiomil)
- nortriptyline (Pamelor, Aventyl)
- protriptyline (Vivactil)
- trimipramine (Surmontil)
